limited human data reveal no teratogenicity at therapeutic doses, yet clinicians are advised to employ the lowest effective regimen
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The requirement for B vitamins varies significantly throughout life, especially during pregnancy, breastfeeding, and as individuals age
While oral supplements can be a way to replace B12, oral supplements dont always absorb in the digestive system
high pharmacologic doses (1-3 g/day) can cause hypotension, insulin resistance, and hepatotoxicity
But including foods high in these vitamins (like whole grains, meats, eggs, dairy, leafy greens, nuts) as tolerated can help maintain levels once the course of injections is over